Tunable dual growth factor delivery from polyelectrolyte multilayer films
نویسندگان
چکیده
منابع مشابه
Tunable dual growth factor delivery from polyelectrolyte multilayer films.
A promising strategy to accelerate joint implant integration and reduce recovery time and failure rates is to deliver a combination of certain growth factors to the integration site. There is a need to control the quantity of growth factors delivered at different times during the healing process to maximize efficacy. Polyelectrolyte multilayer (PEM) films, built using the layer-by-layer (LbL) t...
متن کاملAdvances in polyelectrolyte multilayer nanofilms as tunable drug delivery systems.
There has been considerable interest in polyelectrolyte multilayer nanofilms, which have a variety of applications ranging from optical and electrochemical materials to biomedical devices. Polyelectrolyte multilayer nanofilms are constructed from aqueous solutions using electrostatic layer-by-layer self-assembly of oppositely-charged polyelectrolytes on a solid substrate. Multifunctional polyel...
متن کاملMechanically Responding Functionalized Polyelectrolyte Multilayer Films
The alternate deposition of polyanions and polycations on charged surfaces leads to the formation of nanostructured films called polyelectrolyte multilayers [1,2,3]. The layer by layer deposition process of polyelectrolytes is used to design films equipped by compartments containing "free" polymers or biomolecules [4-6]. Each compartment corresponds to a stratum of an exponentially growing poly...
متن کاملFibronectin adsorption onto polyelectrolyte multilayer films.
The Layer-by-layer deposition of positively and negatively charged macromolecular species is an ideal method for constructing thin films incorporating biological molecules. We investigate the adsorption of fibronectin onto polyelectrolyte multilayer (PEM) films using optical waveguide lightmode spectroscopy (OWLS) and atomic force microscopy (AFM). PEM films are formed by adsorption onto Si(Ti)...
متن کاملTunable synthesis of Prussian Blue in exponentially growing polyelectrolyte multilayer films.
Polyelectrolyte multilayer (PEM) films have become very popular for surface functionalization and the design of functional architectures such as hollow polyelectrolyte capsules. It is known that properties such as permeability to small ionic solutes are strongly dependent on the buildup regime of the PEM films. This permeability can be modified by tuning the ionization degree of the polycations...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biomaterials
سال: 2011
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2011.04.036